Ubuntu Desktop Issue – Super User

I’m using the latest version of Ubuntu 21.04 and on occasion, my screen shows up like the following:

enter image description here

And I can’t get out of it. I’ve tried the escape keys and different alternatives but nothing gets me out except to just reboot. When I mouse over it, all I can do is close each panel. But closing all of them still leaves me in this state. Any ideas on what I’m doing wrong or missing?