user interface – What framework to use for machine learning desktop app?

I want to build a dekstop app that has a UI and runs a machine learning model (ready or one that I will build). The user will input 15 Variables from the UI and the machine learning model will run to give a projection based on those. I also want to create a database that will run on a local server, so many computers that will have this app will be able to connect to it. What frameworks should I use for this project? I’ve seen some frameworks like .NET or UWP, but I want to make sure that I will provide a very nice UI and UX.